약학대학

서울대학교 약학대학 약학과

서울대학교 약학대학 약학과

약학개론 / 약과사회 / 약국관리학 / 약사법규

손성구, 권경희(2014) 국민의 보건권과 안전상비의약품 표시제도, 한국위기관리논집, 10(8) 93-117
조윤숙, 이주연, 권경희(2014) 단일 상급종합병원에서 마약성 진통제의 최근 13년간 사용경향 조사, 약학회지 58(4) 268~276
백진희, 권경희(2013) 의료용 마약류의 국내외 관리지침 비교분석을 통한 마약류의약품의 합리적 관리방안 연구, 병원약사회지 30(2), 141~156

서울대학교 약학대학 제약학과

서울대학교 약학대학 약학과

약제학 / 의약품품질과학 / 약물송달학 / 생물약제학특론

제제학, 한국약학교육협의회 약제학분과회, 신일북스, 2013.
생물약제학과 약동학, 한국약학교육협의회 약제학분과회, 신일북스, 2013.
염류의약품 (역서), 한효경 외, 신일북스, 2013.

Lee SH, Song JG, Han HK. Site-selective oral delivery of therapeutic antibodiesto the inflamed colon via a folic acid-graftedorganic/inorganic hybrid nanocomposite system. Acta Pharm Sin B. 12(11):4249-4261, 2022.
Song JG, Lee SH, Han HK. Development of an M celltargeted nanocomposite system for effective oral protein delivery: preparation,in vitro and in vivo characterization. J Nanobiotechnol. 19(1):15, 2021.
Lee SH, Back SY, Song JG, Han HK. Enhanced oral delivery ofinsulin via the colon-targeted nanocomposite system of organoclay/glycol-chitosan/Eudragit®S100. J Nanobiotechnol. 18(1):104, 2020.
Lee SH, Song JG, Han HK. Development of pH-responsive organic-inorganic hybrid nanocomposites asan effective oral delivery system of protein drugs. J Control Release. 311-312:74-84, 2019.

서울대학교 약학대학 제약학과

서울대학교 약학대학 약학과

생화학 / 분자생물학 / 세포생물학 / 종양생물학특론

Lee CH, Role of serotonin in melanogenesis in the skin. In Serotonin: Biosynthesis, Regulation, and Health Implication (FS Hall Ed), Nova publishing, Canada, 2013.
약품생화학 분자생물학 총정리, 제 1판, 약품생화학 분자생물학분과위원회 편, 신일서적(주), 2015

Cho MH, Park JH, Choi HJ, Park MK, Won HY, Park YJ, Lee CH, Oh SH, Song YS, Kim HS, Oh YA, Lee JY, Kong G. (2015) DOT1L cooperates with c-Myc/p300 complex to epigenetically derepress CDH1 transcription factors in breast cancer progression. Nature Comm. 6:7821
Choi HJ, Park JH, Park MK, Lee CH, Lee JY, Kong G. (2015) UTX induces epigenetic silencing of CDH1 transcription factors by cooperating with LSD1 and HDAC1. EMBO reports 16: 1288-1298
Lee JY, Park MK, Park JH, Lee HJ, Shin DH, Kang Y, Lee CH, Kong G. (2014) Loss of the polycomb protein Mel-18 enhances the epithelial-mesenchymal transition by ZEB1 and ZEB2 expression. through the downregulation of miR-205 in breast cancer. Oncogene, 33:1325-35.

이화여자대학교 약학대학 약학과

서울대학교 약학대학 약학과

약품제조화학 / 의약화학 / 물리유기약품화학 / 의약품설계학

의약화학, 의약화학 편집위원회, 신일북스, 2011.

Lee K, Ban HS, Naik R, Hong YS, Son S, Kim BK, Xia Y, Song KB, Lee HS, Won M. (2013) Target identification of the HIF inhibitor LW6 using multifunctional chemical probes. Angew. Chem. Int., 125:10476-79.
Naik R, Won M, Kim BK, Xia Y, Choi HK, Jin G, Jung Y, Kim HM, Lee K. (2012) Synthesis and structure–activity relationship of (E)-phenoxyacrylic amide derivatives as hypoxia-inducible factor (HIF) 1α inhibitors. J. Med. Chem., 55:10564-71.
Lee J, Xia Y, Son MY, Jin G, Seol B, Kim MJ, Son MJ, Do M, Lee M, Kim D, Lee K, Cho YS. (2012) A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluriotent stem cells. Angew. Chem., 124:12677-81.

2000-2001 Postdoctoral Fellow
Laboratory of Bioorganic Chemistry (Dr. Kenneth A. Jacobson), NIDDK, NIH, Bethesda, MD, USA
2001-2004 Postdoctoral Fellow
Laboratory of Medicinal Chemistry (Dr. Terrence R. Burke, Jr.), Center for Cancer Research, NCI, Frederick, MD, USA
2004-2008 Adjunct Associate Professor
Biomolecular Sciences, University of Science and Technology (UST)
2004-2008 Senior Research Scientist
Molecular Cancer Research Center, Division of Drug Discovery, Korea Research Institute of Bioscience and Biotechnology (KRIBB)
2009 Principal Investigator
Molecular Cancer Research Center, Division of Drug Discovery, Korea Research Institute of Bioscience and Biotechnology (KRIBB)
2012-present Director
Open Translational Research Center for Innovative Drug

서울대학교 약학대학 약학과

서울대학교 약학대학 약학과

예방약학 / 독성학 / 임상독성학 / 지역약국실무실습

예방약학, 제6판, 한국약학교육협의회 예방약학분과회, 신일북스, 2011.
독성학-생명, 환경, 생태계 (역서), 한국약학교육협의회 예방약학분과회, 신일북스, 2008.
건강기능식품학, 제3판, 한국약학교육협의회 예방약학분과회, 신일북스, 2013.

Oh SJ, Kim H, Liu Y, Han HK, Kwon K, Chang KH, Park K, Kim Y, Shim K, An SS, Lee MY. (2014) Incompatibility of silver nanoparticles with lactate dehydrogenase leakage assay for cellular viability test is attributed to protein binding and reactive oxygen species generation. Toxicol. Lett., 225:422-32.
Liu Y, Oh SJ, Chang KH, Kim YG, Lee MY. (2013) Antiplatelet effect of AMP-activated protein kinase activator and its potentiation by the phosphodiesterase inhibitor dipyridamole. Biochem. Pharmacol., 86:914-25.
Kim H, Oh SJ, Kwak HC, Kim JK, Lim CH, Yang JS, Park K, Kim SK, Lee MY. (2012) The impact of intratracheally instilled carbon black on the cardiovascular system of rats: elevation of blood homocysteine and hyperactivity of platelets. J. Toxicol. Environ. Health A., 75:1471-83.

중앙대학교 약학대학 제약학과

중앙대학교 약학대학 약학과

제제학 / 제약공정 / 향장품학

Jeong SH, Lee J, Wee JS. Chap. 10 Fast Disintegrating Tablets. In Oral Controlled Release Formulation Design and Drug Delivery (H Wen and K Park Ed.), John Wiley & Sons, New Jersey, 2010.
Jeong SH, Park JH, Park K. Chap. 2 Formulation Issues around Lipid-based Oral and Parenteral Delivery Systems. In Role of Lipid Excipients in Modifying Oral and Parenteral Drug Delivery: Basic Principoles and Biological Examples (KM Wasan Ed.), John Wiley & Sons, New Jersey, 2007.
Jeong SH, Yourong Fu, Park K. Chap. 4 Hydrogels for Oral. In Polymeric Drug Delivery Systems (GS Kwon Ed.), Taylor & Francis, New York, 2005.

Choi DH, Kim KH, Park JS, Park K, Jeong SH. (2013) Evaluation of drug delivery profiles in geometric three-layered tablets with various mechanical properties, in vitro–in vivo drug release, and Raman imaging, J. Control. Release, 172:763-772.
Kim NA, Lim DG, Lim JY, Kim KH, Jeong SH (2014) Comprehensive evaluation of etanercept stability in various concentrations with biophysical assessment, Int. J. Pharm., 460:108-118.
Nha VT, Shin S, Jeong SH (2013) Lexicographical dynamic goal programming approach to a robust design optimization within the pharmaceutical environment, Eur. J. Oper. Res., 229:505-517.

서울대학교 약학대학 제약학과

서울대학교 약학대학 약학과

의약화학 / 약물유전체학 / 무기화학 / 약품분석화학

의약품합성학, 의약품합성학편집위원회, 동명사, 2014.
의약화학, 의약화학 편집위원회, 신일북스, 2014.

Kim Y-W, Hilinski GJ, Hong J, Kutchukian PS, Crenshaw CM, Berkovitch SS, Chang A, Ham S, Verdine GL. (2014) Stitched α-helical peptides via Bis Ring-Closing Metathesis. J. Am. Chem. Soc., 136:12314-22.
Pham TK, Kim D-H, Lee B-J, Kim Y-W. (2013) Truncated and constrained helical analogs of antimicrobial esculentin-2EM. Bioorg. Med. Chem. Lett., 23:6717-20.
Kim Y-W, Grossman TN, Verdine GL. (2011) Synthesis of all-hydrocarbon stapled α-helical peptides via ring-closing metathesis. Nature Protocols, 6:761-71.

2009-2011 Project Manager
Harvard University, Dept. of Stem Cell & Regenerative Biology, Cambridge, MA, USA

2007-2009 Scientific Associate
Dana-Farber Cancer Institute, Dept. of Cancer Biology, Boston, MA, USA

2003-2007 Postdoctoral Fellow
Harvard University, Dept. of Chemistry & Chemical Biology, Cambridge, MA, USA

1992-1998 Senior Researcher
SK Chemicals, Ltd. Life Science Research Center, Suwon, Gyeonggi-Do, Korea

서울대학교 약학대학 제약학과

서울대학교 약학대학 약학과

유기약화학 / 약품제조화학 / 의약품정보학 / 신약개발특론

의약품합성학, 수정판, 의약품합성학 편집위원회, 동명사, 2013.
의약화학, 4판, 의약화학 편집위원회, 신일서적, 2014.
실험의약품합성학, 1판, 실험의약품합성학 편찬위원회, 청문각, 2013.

Choi WJ, Ko YJ, Kim HO, Chandra G, Lee HW, Koh HJ, Moon HR, Jung YH, Jeong LS. (2012) Stereoselective synthesis of conformationally restricted 2′-C-substituted carbocyclic nucleosides as potential antiviral agents, Tetrahedron, 68:1253-61.
Choi WJ, Chung H-J, Chandra G, Alexander V, Zhao LX, Lee HW, Nayak A, Majik MS, Kim HO, Kim JH, Lee YB, Ahn CH, Lee SK, Jeong LS. (2012) Fluorocyclopentenyl-cytosine with broad spectrum and potent antitumor activity, J. Med. Chem., 55:4521-5.
Yu J, Kim J-H, Lee HW, Alexander V, Ahn H-A, Choi WJ, Choi J, Jeong LS. (2013) New RNA purine building blocks, 4’-Selenopurine nucleosides: first synthesis and unusual mixture of sugar puckerings, Chemistry-a European Journal, 19:5528-32.

서울대학교 약학대학 제약학과

서울대학교 약학대학 약학과

약품생화학 / 종양학 / 단백질생화학 / 기초생리학

Keum YS, Suppression of prostate carcinogenesis by dietary isothiocyanates. In Inflammation, Oxidative Stress, and Cancer (AN Kong Ed), pp. 463-476, CRC Press, Boca Raton, FL, USA, 2014.
Keum YS, Choi BY. (2014) Molecular and chemical regulation of the Keap1-Nrf2 signaling pathway. Molecules, 19(7):10074-89.
Keum YS, Kim HG, Bode AM, Surh YJ, Dong Z. (2013) UVB-induced COX-2 expression requires histone H3 phosphorylation at Ser10 and Ser28, Oncogene, 32(4):444-52.
Keum YS, Jeong YJ. (2012) Development of chemical inhibitors of the SARS coronavirus: viral helicase as a potential target. Biochem. Pharm., 84:1351-58.

서울대학교 약학대학 제약학과

서울대학교 약학대학 약학과

물리약학 / 의약품분석학 / 생물의약품학

마틴의 물리약학, 제6판, 물리약학분과회, 신일북스, 2013.

Yu TK, Shin SA, Kim EH, Kim S, Ryu KS, Cheong H, Ahn HC, Jon S, Suh JY. (2014) An unusual protein-protein interaction through coupled unfolding and binding, Angew. Chem. Int. Ed. Engl., 53:9784-7.
Park TJ, Kim JS, Ahn HC, Kim Y. (2011) Solution and solid-state NMR structural studies of antimicrobial peptides LPcin-I and LPcin-II, Biophys. J., 101:1193-201.
Lim J, Son WS, Park JK, Kim EE, Lee BJ, Ahn HC. (2011) Solution structure of UIM and interaction of tandem ubiquitin binding domains in STAM1 with ubiquitin, Biochem. Biophys. Res. Commun., 405:24-30.

서울대학교 / 약학대학 / 약학과

약품미생물학 / 면역학 / 의약학 영어 / 항생물질학

약품미생물학 요약 및 연습, 제1판, 한국약학교육협의회 감염미생물 면역약학 분과회, 라이프사이언스, 2014.
Lee C, Laimins L. The differentiation-dependent life cycle of human papillomaviruses, In The Papillomaviruses (D. DiMaio and R. Garcia Eds), Springer, First edition, pp. 45-58, 2007.

Cho M, Kim YM, Lee S, Chin YW, Lee C. (2014) Mangosteen xanthones suppress hepatitis C virus genome replication. Virus Genes., 49:208-22.
Cho M, Lee S, Cho T, Lee C. (2014) Roles of the PDZ domain-binding motif of the human papillomavirus type 16 E6 on the immortalization and differentiation of primary human foreskin keratinocytes. Virus Genes., 48: 224-32.
Lee C. (2013) Daclatasvir: potential role in hepatitis C. Drug Des Devel Ther., 7:1223-33.

Postdoctoral researcher at Stanford University School of Medicine, Stanford, California, May 2005 to Dec 2008
Postdoctoral researcher at Roche Pharmaceutical in Palo Alto, Jan 2009 to Dec 2010

서울대학교 약학대학 제약학과

서울대학교 약학대학 약학과

약물학 / 약동학 / 약물치료학 / 임상약동학

약리학, 신일서적, 2021
약물작용과 기본이론, 군자출판사, 2015
신경정신약리학: 뇌와 약물남용, 제2판, 신일서적, 2014

Choi YH, Zhang C, Liu Z, Tu MJ, Yu AX, Yu AM*. A Novel Integrated Pharmacokinetic-Pharmacodynamic Model to Evaluate Combination Therapy and Determine In Vivo Synergism. J Pharmacol Exp Ther. 2021 Jun;377(3):305-315
Yu AM*, Choi YH*, Tu MJ. RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges. Pharmacol Rev. 2020 Oct;72(4):862-898
Han SY, Choi YH*. Pharmacokinetic Interaction between Metformin and Verapamil in Rats: Inhibition of the OCT2-Mediated Renal Excretion of Metformin by Verapamil. Pharmaceutics. 2020 May 21;12(5):468
Han SY, Chae HS, You BH, Chin YW, Kim H, Choi HS, Choi YH*. Lonicera japonica extract increases metformin distribution in the liver without change of systemic exposed metformin in rats. J Ethnopharmacol. 2019 Jun 28;238:111892

성균관대학교 약학대학 약학부

약물치료학 / 의약품정보학 / 소아 및 노인약학 / 병원약국실무실습

2022 최신 임상약료학, 한국임상약학회, 신일북스, 2022
약리학, 제15판, 한국약학교육협의회 약리학분과회, 신일서적, 2022
약물치료학, 제5개정판, 한국임상약학회, 신일북스, 2021

Lee HS, Heo CU, Song YH, Lee K, Choi CI. (2023) Naringin promotes fat browning mediated by UCP1 activation via the AMPK signaling pathway in 3T3-L1 adipocytes. Arch. Pharm. Res., 46:192-205.
Lim SH, Lee HS, Han HK, Choi CI. (2021) Saikosaponin A and D Inhibit Adipogenesis via the AMPK and MAPK Signaling Pathways in 3T3-L1 Adipocytes. Int. J. Mol. Sci., 22:11409.
Kim MJ, Byeon JY, Kim YH, Kim SH, Lee CM, Jung EH, Chae WK, Lee YJ, Jang CG, Lee SY, Choi CI. (2018) Effect of the CYP2D6*10 allele on the pharmacokinetics of clomiphene and its active metabolites. Arch. Pharm. Res., 41:347-53.

서울대학교 약학대학 학사

서울대학교 약학대학 석사

생약학1,2 , 천연물의약품학

Kim HW, Wang M., Leber CA, Nothias L-F, Reher R, Kang KB, Hooft JJ, Dorrestein PC, Gerwick WH, Cottrell GW. (2021) NPClassifier: A Deep Neural Network-Based Structural Classification Tool for Natural Products. J. Nat. Prod. 84 (11), 2795-2807
Kim HW, Park EJ, Cho HM, An JP, Chin YW, Kim J, Sung SH, Oh WK. (2020) Glucose uptake-stimulating galloyl ester triterpenoids from Castanopsis sieboldii. J. Nat. Prod. 83 (10), 3093-3101.
Reher R, Kim HW (Co-first), Zhang C, Mao HH, Wang M, Nothias L-F, Caraballo-Rodriguez AM, Glukhov E, Teke B, Leao T, Alexander KL, Duggan BM, Van Everbroeck EL, Dorrestein PC, Cottrell GW, Gerwick WH, (2020) A convolutional neural network-based approach for the rapid annotation of molecularly diverse natural products. J. Am.Chem. Soc. 142 (9), 4114-4120.

2018.03 ~ 2019.02 서울대학교 약학대학 연수 연구원
2019.04 ~ 2022.02 Scripps Institution of Oceanography, University of California San Diego 박사후연구원